Epigenetic landscapes explain partially reprogrammed cells and identify key reprogramming genes.
A common metaphor for describing development is a rugged "epigenetic landscape" where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing epigenetic landscapes that combines genomic data wi...
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Autores principales: | Alex H Lang, Hu Li, James J Collins, Pankaj Mehta |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/8a4fd51465244b7eabf47a56bd2bd5d2 |
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