Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy

Objective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therap...

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Autores principales:	Young Min Moon PhD, Sang Il Bae PhD, Moo Jae Han PhD, Wan Jeon MD, Tosol Yu MD, Chul Won Choi MD, PhD, Jin Young Kim PhD
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/8a59da70025e454796d2a2fc22467351
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spelling	oai:doaj.org-article:8a59da70025e454796d2a2fc224673512021-12-02T01:04:04ZCorrelation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy1533-033810.1177/15330338211059937https://doaj.org/article/8a59da70025e454796d2a2fc224673512021-11-01T00:00:00Zhttps://doi.org/10.1177/15330338211059937https://doaj.org/toc/1533-0338Objective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therapy (VMAT) plans were generated using pelvic lymph node metastatic prostate cancer patient's data which is sensitive to MLC position errors as they involve several long, narrow, irregular fields. The ASW for each VMAT plan was calculated using our own code developed using Visual Basic for Applications (VBA). The gamma passing rate of the VMAT plan according to the MLC position error was evaluated using ArcCHECK (Sun Nuclear, Melbourne, FL, USA) while inducing symmetric MLC position errors in 0.25 mm intervals from −1 mm to +1 mm in the infinity medical linear accelerator (Elekta AB, Stockholm, Sweden). Finally, we examined the correlation between the change in the passing rate ( γ gradient ) due to the MLC position error and the ASW in VMAT through linear regression analysis using the least squares method. Results: The ASW and γ gradient were found to have a linear correlation according to the MLC position error, and the coefficient of determination was 0.88. For a 1 mm position error of MLC in VMAT, the gamma passing rate improved by approximately 11.9% as the ASW increased by 10 mm. Conclusion: These results are expected to be employed as guidelines to minimize the dose uncertainty due to MLC position error in VMAT.Young Min Moon PhDSang Il Bae PhDMoo Jae Han PhDWan Jeon MDTosol Yu MDChul Won Choi MD, PhDJin Young Kim PhDSAGE PublishingarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENTechnology in Cancer Research & Treatment, Vol 20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
description	Objective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therapy (VMAT) plans were generated using pelvic lymph node metastatic prostate cancer patient's data which is sensitive to MLC position errors as they involve several long, narrow, irregular fields. The ASW for each VMAT plan was calculated using our own code developed using Visual Basic for Applications (VBA). The gamma passing rate of the VMAT plan according to the MLC position error was evaluated using ArcCHECK (Sun Nuclear, Melbourne, FL, USA) while inducing symmetric MLC position errors in 0.25 mm intervals from −1 mm to +1 mm in the infinity medical linear accelerator (Elekta AB, Stockholm, Sweden). Finally, we examined the correlation between the change in the passing rate ( γ gradient ) due to the MLC position error and the ASW in VMAT through linear regression analysis using the least squares method. Results: The ASW and γ gradient were found to have a linear correlation according to the MLC position error, and the coefficient of determination was 0.88. For a 1 mm position error of MLC in VMAT, the gamma passing rate improved by approximately 11.9% as the ASW increased by 10 mm. Conclusion: These results are expected to be employed as guidelines to minimize the dose uncertainty due to MLC position error in VMAT.
format	article
author	Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD
author_facet	Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD
author_sort	Young Min Moon PhD
title	Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
title_short	Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
title_full	Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
title_fullStr	Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
title_full_unstemmed	Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
title_sort	correlation between average segment width and gamma passing rate as a function of mlc position error in volumetric modulated arc therapy
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/8a59da70025e454796d2a2fc22467351
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_version_	1718403329804992512

Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy

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