Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype.
Marek's disease virus (MDV) is an alphaherpesvirus that causes immunosuppression and deadly lymphoma in chickens. Lymphoid organs play a central role in MDV infection in animals. B-cells in the bursa of Fabricius facilitate high levels of MDV replication and contribute to dissemination at early...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/8a68d4424bbf46c2967747934bbdafb5 |
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