Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype.

Marek's disease virus (MDV) is an alphaherpesvirus that causes immunosuppression and deadly lymphoma in chickens. Lymphoid organs play a central role in MDV infection in animals. B-cells in the bursa of Fabricius facilitate high levels of MDV replication and contribute to dissemination at early...

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Autores principales: Laëtitia Trapp-Fragnet, Julia Schermuly, Marina Kohn, Luca D Bertzbach, Florian Pfaff, Caroline Denesvre, Benedikt B Kaufer, Sonja Härtle
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/8a68d4424bbf46c2967747934bbdafb5
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