SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort.
<h4>Background</h4>Severe alpha1-antitrypsin (AAT) deficiency is a strong risk factor for COPD. But the impact of gene variants resulting in mild or intermediate AAT deficiency on the longitudinal course of respiratory health remains controversial. There is indication from experimental s...
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Autores principales: | , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/8a8db7f7e3fa49bfa3d0094019fde0c5 |
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