A dose-escalating toxicology study of the candidate biologic ELP-VEGF

Abstract Vascular Endothelial Growth Factor (VEGF), a key mediator of angiogenesis and vascular repair, is reduced in chronic ischemic renal diseases, leading to microvascular rarefaction and deterioration of renal function. We developed a chimeric fusion of human VEGF-A121 with the carrier protein...

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Bibliographic Details
Main Authors: Jamarius P. Waller, Stephen P. Burke, Jason Engel, Alejandro R. Chade, Gene L. Bidwell
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/8a90e0ab576444fa94b0057516ab228f
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