Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes.

Endocannabinoids regulate energy balance and lipid metabolism by stimulating the cannabinoid receptor type 1 (CB1). Genetic deletion and pharmacological antagonism have shown that CB1 signaling is necessary for the development of obesity and related metabolic disturbances. However, the sufficiency o...

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Auteurs principaux: Maxwell A Ruby, Daniel K Nomura, Carolyn S S Hudak, Anne Barber, John E Casida, Ronald M Krauss
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
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Accès en ligne:https://doaj.org/article/8acb5e7fb5eb45249977d8bed006fa11
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