Sustained induction of collagen synthesis by TGF-β requires regulated intramembrane proteolysis of CREB3L1.
CREB3L1 (cAMP response element binding protein 3-like 1), a transcription factor synthesized as a membrane-bound precursor and activated through Regulated Intramembrane Proteolysis (RIP), is essential for collagen production by osteoblasts during bone development. Here, we show that TGF-β (transform...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2014
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/8adbf80cb35a400ebdc815c92ce9351f |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|