Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation.
Embryonic axis formation in vertebrates is initiated by the establishment of the dorsal Nieuwkoop blastula organizer, marked by the nuclear accumulation of maternal β-catenin, a transcriptional effector of canonical Wnt signaling. Known regulators of axis specification include the canonical Wnt path...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/8afb28dbe1b7438ca0bf4755aabbdef0 |
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