Genotype-Dependent Immunogenicity of Dengue Virus Type 2 Asian I and Asian/American Genotypes in Common Marmoset (<i>Callithrix jacchus)</i>: Discrepancy in Neutralizing and Infection-Enhancing Antibody Levels between Genotypes

Genotype-Dependent Immunogenicity of Dengue Virus Type 2 Asian I and Asian/American Genotypes in Common Marmoset (<i>Callithrix jacchus)</i>: Discrepancy in Neutralizing and Infection-Enhancing Antibody Levels between Genotypes

Owing to genotype-specific neutralizing antibodies, analyzing differences in the immunogenic variation among dengue virus (DENV) genotypes is central to effective vaccine development. Herein, we characterized the viral kinetics and antibody response induced by DENV type 2 Asian I (AI) and Asian/Amer...

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Auteurs principaux: Nor Azila Muhammad Azami, Meng Ling Moi, Yasushi Ami, Yuriko Suzaki, Satoshi Taniguchi, Shigeru Tajima, Masayuki Saijo, Tomohiko Takasaki, Ichiro Kurane, Chang-Kweng Lim
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
dengue
common marmoset
neutralizing antibody
genotypes
FcγR-expressing BHK cells
infection-enhancing
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/8b045d0ea8134f1d9ae4d1c1dac49f35
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https://doaj.org/article/8b045d0ea8134f1d9ae4d1c1dac49f35

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