Sildenafil Citrate Downregulates PDE5A mRNA Expression in Women with Recurrent Pregnancy Loss without Altering Angiogenic Factors—A Preliminary Study

In our previous study, we showed that sildenafil citrate (SC), a selective PDE5A blocker, modulated NK cell activity in patients with recurrent pregnancy loss, which correlated with positive pregnancy outcomes. It was found that NK cells had a pivotal role in decidualization, angiogenesis, spiral ar...

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Autores principales: Monika Kniotek, Aleksander Roszczyk, Michał Zych, Małgorzata Wrzosek, Monika Szafarowska, Radosław Zagożdżon, Małgorzata Jerzak
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/8b1d03903ad149e29fd0539aedbc7c31
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