Struggle To Survive: the Choir of Target Alteration, Hydrolyzing Enzyme, and Plasmid Expression as a Novel Aztreonam-Avibactam Resistance Mechanism

ABSTRACT Aztreonam-avibactam is a promising antimicrobial combination against multidrug-resistant organisms, such as carbapenemase-producing Enterobacterales. Resistance to aztreonam-avibactam has been found, but the resistance mechanism remains poorly studied. We recovered three Escherichia coli is...

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Bibliographic Details
Main Authors: Ke Ma, Yu Feng, Alan McNally, Zhiyong Zong
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
CMY
Online Access:https://doaj.org/article/8b8a6d6f89f34d0c83729370bf6299fc
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