Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis

Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis

Transcoelomic spread of serous ovarian cancer (SOC) results from the cooperative interactions between cancer and host components. Tumor-derived factors might allow the conversion of mesothelial cells (MCs) into tumor-associated MCs, providing a favorable environment for SOC cell dissemination. Howev...

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Detalles Bibliográficos
Autores principales: Danila Del Rio, Ilenia Masi, Valentina Caprara, Francesca Spadaro, Flavia Ottavi, Raffaele Strippoli, Pilar Sandoval, Manuel López-Cabrera, Ricardo Sainz de la Cuesta, Anna Bagnato, Laura Rosanò
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
mesothelial cells
endothelin-1
serous ovarian cancer
β-arrestin1
mesothelial-to-mesenchymal transition
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/8ba8c39e586b4cab9c01eff91032d392
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https://doaj.org/article/8ba8c39e586b4cab9c01eff91032d392

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