Highly selective nickel-catalyzed gem-difluoropropargylation of unactivated alkylzinc reagents
Difluoroalkylated compounds find wide application in medicinal chemistry. Here, the authors describe the mild nickel-catalyzed difluoroalkylation of aliphatic alkylzinc reagents with gem-difluoropropargylbromides and show its utility in a number of post-synthetic transformations.
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/8baa04f025c24df1820a6e3364a04101 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|