Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients

Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients

Abstract Patients with HBeAg-negative chronic infection (CI) have not been extensively studied because of low viremia. The HBx protein, encoded by HBX, has a key role in viral replication. Here, we analyzed the viral quasispecies at the 5′ end of HBX in CI patients and compared it with that of patie...

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Main Authors: Maria Francesca Cortese, Carolina González, Josep Gregori, Rosario Casillas, Luca Carioti, Mercedes Guerrero-Murillo, Mar Riveiro-Barciela, Cristina Godoy, Sara Sopena, Marçal Yll, Josep Quer, Ariadna Rando, Rosa Lopez-Martinez, Beatriz Pacín Ruiz, Selene García-García, Rafael Esteban-Mur, David Tabernero, Maria Buti, Francisco Rodríguez-Frías
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/8bae6b63e6994cb78433411466be5879
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https://doaj.org/article/8bae6b63e6994cb78433411466be5879

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