High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices

Abstract We systematically analyzed the relative contributions of frequency component elements of hemodynamic shear stress waveforms encountered in cardiovascular blood recirculating devices as to overall platelet activation over time. We demonstrated that high frequency oscillations are the major d...

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Autores principales: Filippo Consolo, Jawaad Sheriff, Silvia Gorla, Nicolò Magri, Danny Bluestein, Federico Pappalardo, Marvin J. Slepian, Gianfranco B. Fiore, Alberto Redaelli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8bd3bad9a89347f49a85d7408c347b66
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