Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response

For many intracellular pathogens, the phagosome is the site of events and interactions that shape infection outcome. Phagosomal membrane damage, in particular, is proposed to benefit invading pathogens. To define the innate immune consequences of this damage, we profiled macrophage transcriptional r...

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Autores principales: Amelia E Hinman, Charul Jani, Stephanie C Pringle, Wei R Zhang, Neharika Jain, Amanda J Martinot, Amy K Barczak
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
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Acceso en línea:https://doaj.org/article/8c1f5d008f2d40cf98b98547ff9c2bfb
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