Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response

For many intracellular pathogens, the phagosome is the site of events and interactions that shape infection outcome. Phagosomal membrane damage, in particular, is proposed to benefit invading pathogens. To define the innate immune consequences of this damage, we profiled macrophage transcriptional r...

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Auteurs principaux: Amelia E Hinman, Charul Jani, Stephanie C Pringle, Wei R Zhang, Neharika Jain, Amanda J Martinot, Amy K Barczak
Format: article
Langue:EN
Publié: eLife Sciences Publications Ltd 2021
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Accès en ligne:https://doaj.org/article/8c1f5d008f2d40cf98b98547ff9c2bfb
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