Selective DNAM-1 expression on small peritoneal macrophages contributes to CD4+ T cell costimulation

Abstract Mouse peritoneal macrophages consist of two subsets: large peritoneal macrophages (LPMs) and small peritoneal macrophages (SPMs), defined as CD11bhiF4/80hi and CD11b+F4/80lo cells, respectively. We reveal that SPMs, but not LPMs, have the ability to present antigens to naïve CD4+ T cells. C...

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Autores principales: Eri Takenaka, Anh Van Vo, Yumi Yamashita-Kanemaru, Akira Shibuya, Kazuko Shibuya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8c34dccbeeeb4050956e420ac25b6467
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