A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus

The coordination of interactions between multiple regulatory elements and genes within a chromatin domain remains poorly understood. Here, the authors use a method to detect multi-way chromatin interactions in a mouse model in which the α-globin domain is extended to include several additional genes...

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Auteurs principaux: A. Marieke Oudelaar, Caroline L. Harrold, Lars L. P. Hanssen, Jelena M. Telenius, Douglas R. Higgs, Jim R. Hughes
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/8c56dab7a74b4c60ab85d1cab13fd72b
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