Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation

Early-life adversity is thought to increase the risk of psychopathology through epigenetic mechanisms. Here, the authors profile 6 histone marks, chromatin states and DNA methylation in the lateral amygdala in subjects with a history of early-life adversity.

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Autores principales:	Pierre-Eric Lutz, Marc-Aurèle Chay, Alain Pacis, Gary G. Chen, Zahia Aouabed, Elisabetta Maffioletti, Jean-François Théroux, Jean-Christophe Grenier, Jennie Yang, Maria Aguirre, Carl Ernst, Adriana Redensek, Léon C. van Kempen, Ipek Yalcin, Tony Kwan, Naguib Mechawar, Tomi Pastinen, Gustavo Turecki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8c5757658d8b418787c5d3069801d997
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spelling	oai:doaj.org-article:8c5757658d8b418787c5d3069801d9972021-12-02T14:03:40ZNon-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation10.1038/s41467-021-21365-32041-1723https://doaj.org/article/8c5757658d8b418787c5d3069801d9972021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21365-3https://doaj.org/toc/2041-1723Early-life adversity is thought to increase the risk of psychopathology through epigenetic mechanisms. Here, the authors profile 6 histone marks, chromatin states and DNA methylation in the lateral amygdala in subjects with a history of early-life adversity.Pierre-Eric LutzMarc-Aurèle ChayAlain PacisGary G. ChenZahia AouabedElisabetta MaffiolettiJean-François ThérouxJean-Christophe GrenierJennie YangMaria AguirreCarl ErnstAdriana RedensekLéon C. van KempenIpek YalcinTony KwanNaguib MechawarTomi PastinenGustavo TureckiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pierre-Eric Lutz Marc-Aurèle Chay Alain Pacis Gary G. Chen Zahia Aouabed Elisabetta Maffioletti Jean-François Théroux Jean-Christophe Grenier Jennie Yang Maria Aguirre Carl Ernst Adriana Redensek Léon C. van Kempen Ipek Yalcin Tony Kwan Naguib Mechawar Tomi Pastinen Gustavo Turecki Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
description	Early-life adversity is thought to increase the risk of psychopathology through epigenetic mechanisms. Here, the authors profile 6 histone marks, chromatin states and DNA methylation in the lateral amygdala in subjects with a history of early-life adversity.
format	article
author	Pierre-Eric Lutz Marc-Aurèle Chay Alain Pacis Gary G. Chen Zahia Aouabed Elisabetta Maffioletti Jean-François Théroux Jean-Christophe Grenier Jennie Yang Maria Aguirre Carl Ernst Adriana Redensek Léon C. van Kempen Ipek Yalcin Tony Kwan Naguib Mechawar Tomi Pastinen Gustavo Turecki
author_facet	Pierre-Eric Lutz Marc-Aurèle Chay Alain Pacis Gary G. Chen Zahia Aouabed Elisabetta Maffioletti Jean-François Théroux Jean-Christophe Grenier Jennie Yang Maria Aguirre Carl Ernst Adriana Redensek Léon C. van Kempen Ipek Yalcin Tony Kwan Naguib Mechawar Tomi Pastinen Gustavo Turecki
author_sort	Pierre-Eric Lutz
title	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
title_short	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
title_full	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
title_fullStr	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
title_full_unstemmed	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
title_sort	non-cg methylation and multiple histone profiles associate child abuse with immune and small gtpase dysregulation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8c5757658d8b418787c5d3069801d997
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Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation

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