The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.
MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent resear...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2008
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Accès en ligne: | https://doaj.org/article/8c6348d8a48d43a3b6460cb98488eec0 |
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