The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.

The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.

MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent resear...

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Autores principales: Wenbin Ye, Qing Lv, Chung-Kwun Amy Wong, Sean Hu, Chao Fu, Zhong Hua, Guoping Cai, Guoxi Li, Burton B Yang, Yaou Zhang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8c6348d8a48d43a3b6460cb98488eec0
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