The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.
MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent resear...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/8c6348d8a48d43a3b6460cb98488eec0 |
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