Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates
Abstract We present the anticancer properties of cis, cis, trans-[Pt(IV)(NH3)2Cl2(OA)2] [Pt(IV)diOA] (OA = octanoato), Pt(IV) derivative of cisplatin containing two OA units appended to the axial positions of a six-coordinate Pt(IV) center. Our results demonstrate that Pt(IV)diOA is a potent cytotox...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/8c8d7ac8a35249ac83c6856771eb6c7d |
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