Expedient syntheses of N-heterocycles via intermolecular amphoteric diamination of allenes

Saturated N-heterocycle rings are common structural motifs of many FDA-approved drugs. Here, the authors show that a metal-free amphoteric diamination of allenes produces valuable six-, seven- and eight-membered N-heterocycles with high diversity and tolerance of functional groups on the ring.

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Autores principales: Zhishi Ye, Sarju Adhikari, Yu Xia, Mingji Dai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8caaea6b48b349a2bd81dbba2adf1081
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