Expedient syntheses of N-heterocycles via intermolecular amphoteric diamination of allenes

Saturated N-heterocycle rings are common structural motifs of many FDA-approved drugs. Here, the authors show that a metal-free amphoteric diamination of allenes produces valuable six-, seven- and eight-membered N-heterocycles with high diversity and tolerance of functional groups on the ring.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhishi Ye, Sarju Adhikari, Yu Xia, Mingji Dai
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/8caaea6b48b349a2bd81dbba2adf1081
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!