Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

The novel 1,2,3-triazolyl-appended <i>N</i>- and <i>O</i>-heterocycles containing amidine <b>4</b>–<b>11</b> and amidoxime <b>12</b>–<b>22</b> moiety were prepared and evaluated for their antiproliferative activities in vitro. A...

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Autores principales: Silvija Maračić, Petra Grbčić, Suresh Shammugam, Marijana Radić Stojković, Krešimir Pavelić, Mirela Sedić, Sandra Kraljević Pavelić, Silvana Raić-Malić
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
amidine
amidoxime
antiproliferative activity
DNA binding
fluorescence
CD spectroscopy
Organic chemistry
QD241-441
Acceso en línea:https://doaj.org/article/8cb32eaeb4324ad7a8d052bd4effcb96
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https://doaj.org/article/8cb32eaeb4324ad7a8d052bd4effcb96

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