Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process

Abstract Nonsteroidal 2-arylproprionic acids are widely used, over-the-counter, anti-inflammatory drugs. Photosensitivity is a commonly overlooked adverse effect of these drugs. Based on the combined use of cell viability assays and molecular modeling, we prove and rationalize the photochemical path...

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Autores principales: Emmanuelle Bignon, Marco Marazzi, Vanessa Besancenot, Hugo Gattuso, Guillaume Drouot, Christophe Morell, Leif A. Eriksson, Stephanie Grandemange, Elise Dumont, Antonio Monari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8cd0d36efdfe450e87b6420ae1b08cf9
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