Inhibition of MRN activity by a telomere protein motif
Telomeres suppress the DNA damage response at chromosome ends. Here the authors show that in budding yeast the activity of the MRX complex in DNA repair and DNA damage signaling is inhibited by telomeric protein Rif2 via a short motif at the N-terminus.
Guardado en:
Autores principales: | Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8cecf44805f740329669d3853d59d8f7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways
por: Vivek Tripathi, et al.
Publicado: (2018) -
The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins
por: Gabrielle J. Grundy, et al.
Publicado: (2016) -
Telomeric RNAs are essential to maintain telomeres
por: Juan José Montero, et al.
Publicado: (2016) -
Telomere length in early childhood is associated with sex and ethnicity
por: Kien Ly, et al.
Publicado: (2019) -
Telomere-to-telomere gapless chromosomes of banana using nanopore sequencing
por: Caroline Belser, et al.
Publicado: (2021)