Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models

Abstract Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. Among the key challenges in developing effective therapeutics is the poor translation of preclinical models used in the drug discovery pipeline. This leaves drug attrition rates and costs at an unacceptably high level....

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Melica Nourmoussavi Brodeur, Kayla Simeone, Kim Leclerc-Deslauniers, Hubert Fleury, Euridice Carmona, Diane M. Provencher, Anne-Marie Mes-Masson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/8cf5cb2dcdec424aabc6b0c6535c4a57
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!