Influenza virus neuraminidase regulates host CD8+ T-cell response in mice

Chung-Yi Wu et al. demonstrate a role of neuraminidase (NA) for Influenza A viruse (IAV)-specific CD8+ T-cell response and virion assembly. When mice are vaccinated with the live attenuated NA-defective IAV, they are protected from the upcoming IAV infection. This study provides insights into the de...

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Autores principales: Chung-Yi Wu, Hong-Yang Chuang, Chi-Huey Wong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8d119900ef2c4a00b2a69ffd6a6d5bb5
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