Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus

Abstract Although the anxiolytic-like effects of Xiaoyaosan, a Chinese herbal formula, have been described in many previous studies, its underlying mechanism remains undefined. The cytokine tumour necrosis factor-α (TNF-α) and its closely associated janus kinase 2 (JAK2)-signal transducer and activa...

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Bibliographic Details
Main Authors: Xiao-Juan Li, Qing-Yu Ma, You-Ming Jiang, Xiao-Hui Bai, Zhi-Yi Yan, Qun Liu, Qiu-Xia Pan, Yue-Yun Liu, Jia-Xu Chen
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/8d43a9d2cccf4975a980bbcd9f7e3d20
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