Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

Abstract In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating lymphocytes (TILs). Although such therapies are, to date, unsuccessful in gliomas, little is known on the immune contexture of TILs in these t...

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Bibliographic Details
Main Authors: Bas Weenink, Kaspar Draaisma, Han Z. Ooi, Johan M. Kros, Peter A. E. Sillevis Smitt, Reno Debets, Pim J. French
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
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Online Access:https://doaj.org/article/8d69b7caf1204a69af1c62b11ef298e8
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