Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

Abstract In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating lymphocytes (TILs). Although such therapies are, to date, unsuccessful in gliomas, little is known on the immune contexture of TILs in these t...

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Autores principales: Bas Weenink, Kaspar Draaisma, Han Z. Ooi, Johan M. Kros, Peter A. E. Sillevis Smitt, Reno Debets, Pim J. French
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8d69b7caf1204a69af1c62b11ef298e8
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