89Zr anti-CD44 immuno-PET monitors  CD44 expression on splenic myeloid cells and HT29 colon cancer cells

Abstract CD44 is a cell-surface glycoprotein involved in cell–cell interaction, adhesion, and migration. CD44 is found on colon cancer cells and on immune cells. Previous studies of 89Zr PET imaging of CD44 have relied on an anti-human antibody (Ab), which can influence biodistribution in murine mod...

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Bibliographic Details
Main Authors: Jin Won Park, Kyung-Ho Jung, Jin Hee Lee, Seung Hwan Moon, Young Seok Cho, Kyung-Han Lee
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/8da0f26256c24d0688b7a7b0d20c887e
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