Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.

<h4>Background</h4>The Wave complex activates the Arp2/3 complex, inducing actin polymerization in lamellipodia and membrane ruffles. The Wave complex is composed of five subunits, the smallest of which, Brick1/Hspc300 (Brk1), is the least characterized. We previously reported that, unli...

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Autores principales: Emmanuel Derivery, Jenny Fink, Davy Martin, Anne Houdusse, Matthieu Piel, Theresia E Stradal, Daniel Louvard, Alexis Gautreau
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/8dc5736ac9304d1b8870b35054f5c809
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