Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.
<h4>Background</h4>The Wave complex activates the Arp2/3 complex, inducing actin polymerization in lamellipodia and membrane ruffles. The Wave complex is composed of five subunits, the smallest of which, Brick1/Hspc300 (Brk1), is the least characterized. We previously reported that, unli...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2008
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| Subjects: | |
| Online Access: | https://doaj.org/article/8dc5736ac9304d1b8870b35054f5c809 |
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