Genome-Wide Polygenic Risk Score for Predicting High Risk Glaucoma Individuals of Han Chinese Ancestry

Genome-Wide Polygenic Risk Score for Predicting High Risk Glaucoma Individuals of Han Chinese Ancestry

Glaucoma is a progressive and irreversible blindness-causing disease. However, the underlying genetic factors and molecular mechanisms remain poorly understood. Previous genome-wide association studies (GWAS) have made tremendous progress on the SNP-based disease association and characterization. Ho...

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Auteurs principaux: Yu-Jer Hsiao, Hao-Kai Chuang, Sheng-Chu Chi, Yung-Yu Wang, Pin-Hsuan Chiang, Pai-Chi Teng, Tung-Mei Kuang, Aliaksandr A. Yarmishyn, Tai-Chi Lin, De-Kuang Hwang, Shih-Jen Chen, Shih-Hwa Chiou, Mei-Ju Chen, Ai-Ru Hsieh, Chih-Chien Hsu
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
glaucoma
genome-wide association studies
polygenic risk score
Asian population
biobank
retrospective study
Medicine
R
Accès en ligne:https://doaj.org/article/8dc8e105b1184138ab966a8335510bc6
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https://doaj.org/article/8dc8e105b1184138ab966a8335510bc6

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