Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation

Abstract Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability wh...

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Autores principales: Virender Kumar Sharma, Mayurika Lahiri
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8dd02fb26ae54f6cadf2d5b862f5c9e0
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