Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation
Abstract Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability wh...
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Autores principales: | Virender Kumar Sharma, Mayurika Lahiri |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/8dd02fb26ae54f6cadf2d5b862f5c9e0 |
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