Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation
Abstract Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability wh...
Enregistré dans:
Auteurs principaux: | Virender Kumar Sharma, Mayurika Lahiri |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/8dd02fb26ae54f6cadf2d5b862f5c9e0 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer
par: Weimei Tang, et autres
Publié: (2019) -
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
par: Sant-Rayn Pasricha, et autres
Publié: (2017) -
HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes
par: Nicoletta Marroncelli, et autres
Publié: (2018) -
Activation of p21 by HDAC inhibitors requires acetylation of H2A.Z.
par: Luca Bellucci, et autres
Publié: (2013) -
E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair
par: Swarnalatha Manickavinayaham, et autres
Publié: (2019)