Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.

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Autores principales: Naoki Hisamoto, Anna Tsuge, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Hiroshi Hanafusa, Kunihiro Matsumoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c4118828
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