Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.
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Nature Portfolio
2018
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oai:doaj.org-article:8dd579fe8d4b4a528c89dbc5c41188282021-12-02T16:49:18ZPhosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration10.1038/s41467-018-05478-w2041-1723https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c41188282018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05478-whttps://doaj.org/toc/2041-1723Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.Naoki HisamotoAnna TsugeStrahil Iv. PastuhovTatsuhiro ShimizuHiroshi HanafusaKunihiro MatsumotoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Naoki Hisamoto Anna Tsuge Strahil Iv. Pastuhov Tatsuhiro Shimizu Hiroshi Hanafusa Kunihiro Matsumoto Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
description |
Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system. |
format |
article |
author |
Naoki Hisamoto Anna Tsuge Strahil Iv. Pastuhov Tatsuhiro Shimizu Hiroshi Hanafusa Kunihiro Matsumoto |
author_facet |
Naoki Hisamoto Anna Tsuge Strahil Iv. Pastuhov Tatsuhiro Shimizu Hiroshi Hanafusa Kunihiro Matsumoto |
author_sort |
Naoki Hisamoto |
title |
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
title_short |
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
title_full |
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
title_fullStr |
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
title_full_unstemmed |
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration |
title_sort |
phosphatidylserine exposure mediated by abc transporter activates the integrin signaling pathway promoting axon regeneration |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c4118828 |
work_keys_str_mv |
AT naokihisamoto phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration AT annatsuge phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration AT strahilivpastuhov phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration AT tatsuhiroshimizu phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration AT hiroshihanafusa phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration AT kunihiromatsumoto phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration |
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1718383347363741696 |