Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.

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Autores principales: Naoki Hisamoto, Anna Tsuge, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Hiroshi Hanafusa, Kunihiro Matsumoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c4118828
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spelling oai:doaj.org-article:8dd579fe8d4b4a528c89dbc5c41188282021-12-02T16:49:18ZPhosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration10.1038/s41467-018-05478-w2041-1723https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c41188282018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05478-whttps://doaj.org/toc/2041-1723Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.Naoki HisamotoAnna TsugeStrahil Iv. PastuhovTatsuhiro ShimizuHiroshi HanafusaKunihiro MatsumotoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Naoki Hisamoto
Anna Tsuge
Strahil Iv. Pastuhov
Tatsuhiro Shimizu
Hiroshi Hanafusa
Kunihiro Matsumoto
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
description Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regeneration in the peripheral nervous system.
format article
author Naoki Hisamoto
Anna Tsuge
Strahil Iv. Pastuhov
Tatsuhiro Shimizu
Hiroshi Hanafusa
Kunihiro Matsumoto
author_facet Naoki Hisamoto
Anna Tsuge
Strahil Iv. Pastuhov
Tatsuhiro Shimizu
Hiroshi Hanafusa
Kunihiro Matsumoto
author_sort Naoki Hisamoto
title Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
title_short Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
title_full Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
title_fullStr Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
title_full_unstemmed Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
title_sort phosphatidylserine exposure mediated by abc transporter activates the integrin signaling pathway promoting axon regeneration
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c4118828
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AT annatsuge phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration
AT strahilivpastuhov phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration
AT tatsuhiroshimizu phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration
AT hiroshihanafusa phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration
AT kunihiromatsumoto phosphatidylserineexposuremediatedbyabctransporteractivatestheintegrinsignalingpathwaypromotingaxonregeneration
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