ProMMP-1 PRODUCTION BY CULTIVATED CELLS OF VASCULAR ENDОTHELIUM IN VITRO AND IN A HUMAN BODY
Abstract. Matrix metalloproteinases (MMP) are structurally related endopeptidase composed of active sites which include ions Zn2+ and Ca2+. Cultured cells of human blood vessels produce MMP-1, proteolytic effect is aimed at splitting the collagen I and III types, and subsequent vascular remodeling....
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Main Authors: | N. N. Scliankina, N. V. Boldyreva, A. A. Babayants, I. S. Frolova, D. L. Belyaev, Yu. A. Portnova, O. N. Scheglovitova |
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Format: | article |
Language: | RU |
Published: |
Sankt-Peterburg : NIIÈM imeni Pastera
2014
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Online Access: | https://doaj.org/article/8dfc60981add4d9db891648d96ccfae3 |
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