Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames

Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames

Cryptic translation of the 'non-coding' genome is increasingly recognised, however its biological significance remains unclear. Laumont et al.employ proteogenomic techniques to map the human immunoproteome, and find that approximately 10% of MHC class I-associated peptides are cryptic.

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Autores principales: Céline M. Laumont, Tariq Daouda, Jean-Philippe Laverdure, Éric Bonneil, Olivier Caron-Lizotte, Marie-Pierre Hardy, Diana P. Granados, Chantal Durette, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8e030826a1744d55a142f5a4d3124d1e
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https://doaj.org/article/8e030826a1744d55a142f5a4d3124d1e

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