Reducing Animal Use with a Biotelemetry-Enhanced Murine Model of Sepsis

Abstract Animal models of sepsis exhibit considerable variability in the temporal development of the physiologic response, which reduces the power of studies, particularly if interventions are tested at arbitrary time points. We developed a biotelemetry-based model of cecal ligation and puncture (CL...

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Autores principales: Anthony Lewis, Brian Zuckerbraun, John Griepentrog, Xianghong Zhang, Matthew Rosengart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8e0a3c8648f7443c8551f9b9f98b732e
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