Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

ABSTRACT Immunization with sporozoites under chloroquine chemoprophylaxis (CPS) induces distinctly preerythrocytic and long-lasting sterile protection against homologous controlled human malaria infection (CHMI). To identify possible humoral immune correlates of protection, plasma samples were colle...

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Bibliographic Details
Main Authors: Joshua M. Obiero, Joseph J. Campo, Anja Scholzen, Arlo Randall, Else M. Bijker, Meta Roestenberg, Cornelus C. Hermsen, Andy Teng, Aarti Jain, D. Huw Davies, Robert W. Sauerwein, Philip L. Felgner
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
CHMI
antibody
malaria
preerythrocytic immunity
protein microarrays
sterile protection
Microbiology
QR1-502
Online Access:https://doaj.org/article/8e165887dd384f20b347b911c8b738d8
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https://doaj.org/article/8e165887dd384f20b347b911c8b738d8

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