TP53 isoform junction reads based analysis in malignant and normal contexts

Abstract TP53 is one of the most frequently altered genes in cancer; it can be inactivated by a number of different mechanisms. NM_000546.6 (ENST00000269305.9) is by far the predominant TP53 isoform, however a few other alternative isoforms have been described to be expressed at much lower levels. T...

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Autores principales: Suleyman Vural, Lun-Ching Chang, Laura M. Yee, Dmitriy Sonkin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8e296f6de39e4f9788c5d915b7962f4c
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