TP53 isoform junction reads based analysis in malignant and normal contexts
Abstract TP53 is one of the most frequently altered genes in cancer; it can be inactivated by a number of different mechanisms. NM_000546.6 (ENST00000269305.9) is by far the predominant TP53 isoform, however a few other alternative isoforms have been described to be expressed at much lower levels. T...
Guardado en:
Autores principales: | Suleyman Vural, Lun-Ching Chang, Laura M. Yee, Dmitriy Sonkin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8e296f6de39e4f9788c5d915b7962f4c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells
por: Selvakumar Anbalagan, et al.
Publicado: (2021) -
Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.
por: Elisabeth Silden, et al.
Publicado: (2013) -
Assessment of TP53 mutations in benign and malignant salivary gland neoplasms.
por: Carolina Cavaliéri Gomes, et al.
Publicado: (2012) -
TP53 in Myelodysplastic Syndromes
por: Yan Jiang, et al.
Publicado: (2021) -
Concurrent ductal carcinoma in-situ and malignant phyllodes with tp53 mutation in an 11-year-old
por: Cameron F. Leveille, et al.
Publicado: (2021)