Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection

Development of a HCV vaccine is hampered by a lack of appropriate small animal models. Here, Hartlage et al. describe a rat model of hepacivirus persistence and show that persistence can be prevented by vaccination with viral non-structural proteins.

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Autores principales: Alex S. Hartlage, Satyapramod Murthy, Arvind Kumar, Sheetal Trivedi, Piyush Dravid, Himanshu Sharma, Christopher M. Walker, Amit Kapoor
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8e3f05a0172441aea2e16eff245c50b0
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