First-line therapy of chronic myeloid leukemia – focus on dasatinib

Philip C AmreinHematology-Oncology, Massachusetts General Hospital, Boston, USAAbstract: Dasatinib is a broad spectrum, ATP-competitive, tyrosine kinase inhibitor with low nM activity against Bcr-Abl, Src, and other tyrosine kinases. This activity has allowed dasatinib to emerge as one of the most e...

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Bibliographic Details
Main Author: Amrein PC
Format: article
Language:EN
Published: Dove Medical Press 2012
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Online Access:https://doaj.org/article/8e4489f7dd2b4887984e6baf19837865
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